Medication-Related Osteonecrosis of the Jaw—A Continuing Issue

Introduction: Medication-related osteonecrosis of the jaw (MRONJ) is a condition that becoming more common in everyday practice both dental and maxillofacial surgeons. Materials methods: This paper aims to provide comprehensive easy read by clinicians presentation comprehensive, accessible, up-to-date data on MRONJ. The individual chapters focus etiology, epidemiology, diagnosis, prevention, treatment, recurrence Results discussion: It has been observed over years among drugs increase risk disease, apart from bisphosphonates, angiogenesis inhibitors anti-RANKL monoclonal antibodies should also be included. A thorough physical subjective examination, periodic correction prostheses, an adequate preparation for even simplest procedures oral cavity area can prevent or minimize Conclusions: extremely difficult treat once it occurs oftentimes recurring problem leads multitude symptoms gradually decrease quality patient’s life.